Acetylspiramycin Tablets for Sensitive Staphylococcus, Streptococcus and Streptococcus Pneumoniae Caused by Light, Moderate Infections

• Name: Acetylspiramycin Tablets
• Transport Package: Carton
• Specification: 20x15x15cm
• Trademark: FUL
• Origin: China
• Model NO.: CF052
• Production Capacity: 100000/Month

Product Description

Acetyl spiramycin tablets

Generic name acetylspiramycin tablets

Main Ingredient Acetylspiramycin.

Indications This product is suitable for sensitive Staphylococcus, Streptococcus and Streptococcus pneumoniae caused by light, moderate infections, such as pharyngitis, tonsillitis, sinusitis, otitis media, periodontitis, acute bronchitis, chronic bronchitis acute attack, pneumonia, non-gonococcal urethritis, skin and soft tissue infection, It can also be used for cryptosporidiosis or as the drug of choice for the treatment of toxoplasmosis in pregnant women.

Adverse reactions The patients had good tolerance to this product, and the main adverse reactions were gastrointestinal reactions such as abdominal pain, nausea, vomiting, etc., which often occurred at large doses of medication, and the degree was mostly mild, and could disappear spontaneously after drug withdrawal. Allergy is rare, mainly drug eruption. No impairment of liver and kidney function and routine abnormality of blood and urine were found.

Contraindications contraindicated in patients allergic to this product, erythromycin and other macrolides.

Precautions 1. Because the hepatobiliary system is the main route for the excretion of acetylspiramycin, patients with severe liver dysfunction should use this product with c

aution.

2. Dose adjustment is not necessary in patients with mild renal insufficiency, but the use of acetylspiramycin in patients with severe renal insufficiency is lacking, so it should be used with caution.

3. If you have an allergic reaction, stop taking the medicine immediately.

Pregnant women and lactating women use this product can penetrate the placenta, so in pregnant women to fully weigh the advantages and disadvantages before deciding whether to use. There is no data showing whether acetylspiramycin is excreted by breast milk, but since many macrolides can be excreted by breast milk, lactating women should use this product with caution and stop breastfeeding if it is necessary.

The efficacy and safety of pediatric drugs within 6 months have not been determined.

Elderly patients with normal liver and kidney function do not need to reduce the amount of medication.

Drug interaction 1. This product does not affect the metabolism of aminophylline and other drugs in vivo.

2. In patients receiving ergotamine derivatives, ergotamine poisoning has occurred when some macrolides are used at the same time. There has been no report of interaction between ergotamine and acetylspiramycin at present, but this possibility still exists in theory, so acetylspiramycin and ergotamine should not be taken simultaneously.

An overdose is unclear.

Toxicol acetylspiramycin is a acetylated derivative of spiramycin and belongs to the 16-memeric macrolides. This product has good antibacterial effect on gram-positive cocci such as staphylococcus aureus, streptococcus pneumoniae, streptococcus pyogenes and enterococcus faecalis. Of listeria genus, catarrh mora bacteria, bacteria neisseria gonorrhea, fetal bending bacterium, haemophilus influenzae, eosinophilic lung legionella, whooping cough bacili, bacteroides, gas capsule bacillus, acne propionic acid bacillus, streptococcus aureus and digestion and chlamydia, mycoplasma, toxoplasma gondii and cryptosporidium, also has the effects of inhibition. Intestinal gram-negative bacilli are usually drug resistant. The mechanism of action is that acetylspiramycin binds to the 50S subunit of the ribosome of sensitive microorganisms to inhibit the synthesis of RNA-dependent proteins and thus exert bacteriostasis.

Pharmacokinetics This product is acid-resistant, oral absorption is good, after gastrointestinal absorption, deacetyl into spiramycin and play an antibacterial role. The peak plasma concentration (Cmax) was 1mg/L 2 hours after a single dose of 0.2g oral administration. This product is widely distributed in the body. The concentration in bile, urine, pus, bronchial secretions, lung tissue and prostate is generally higher than that in blood. This product cannot cross the blood-cerebrospinal fluid barrier. The mean blood elimination half-life (t1/2β) is about 4 ~ 8 hours. There is accumulation in the body after repeated administration. The product is mainly excreted through feces, and the amount of urine excretion in 12 hours is about 5% ~ 15% of the dose, most of which are metabolites, and the concentration in bile can reach 15 ~ 40 times of the blood concentration.

Storage sealed, stored in a cool, dark and dry place.

FAQ
1.who are we?
We are based in Fujian, China, start from 2000,sell to North America(40.00%),Southeast Asia(25.00%),Western Europe(25.00%),Africa(10.00%).There are total about 50 people in our office.

2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;

3.what can you buy from us?
Pharmaceutical production lines,Intermediates,APIs,Finished Drug Preparations & Vaccines.

4. why should you buy from us not from other suppliers?
We have our own manufacture factories and one professional sales team working for the clients all over the world.

5. what services can we provide?
Accepted Delivery Terms: FOB,CIF,EXW,DDP,Express Delivery;
Accepted Payment Currency:USD,EUR,CAD,AUD,GBP,CNY;
Accepted Payment Type: T/T,L/C,PayPal,Western Union;
Language Spoken:English,Chinese,Japanese

Our Ddvantage:
1. Quick delivery
2. Online payment
3. Quality assurance
4. Welcome big order
5. After-sales service 24 hours
6. Competitive advantage products
7. Our value information is "Quality is our culture"
8. Work with us to provide you with secure funds, your business is securely protected, our advantages

Our Service
a)  Free amples can be provided.
b) Guide customers through professional technology and teach them how to use our products after sale
c) Determine the lowest price of high-quality products
1. Skilled experience: Our company is a leading manufacturer of professional production in China pharmaceutical field for many years.
2. The highest quality: to ensure high quality, once any problems are found, the package will be re-shipped for you.
3. Safe transportation: by air express (FedEx, UPS, DHL, EMS). It is recommended that you choose the most professional freight forwarder.
4. Fast delivery: We have stock, so once payment is received, we can deliver quickly.
5. Quality service: We will provide you with enthusiastic after-sales service. If you have any questions, we will reply to youwithin 24 hours.
6. Competitive price: discounts will be obtained when making large orders.

Our Manufacture Factory
Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd is a comprehensive enterprise which integrates R & D, production and construction of pharmaceutical production equipments, development and transfer of biotechnology, and cooperative production and sales of drugs and vaccines. The self-developed pharmaceutical production equipment branded FUL has been put into operation in many well-known pharmaceutical enterprises such as SINOPHARM, CSPC and also cooperates with many well-known pharmaceutical enterprises in production and sales, including pharmaceutical intermediates, APIs and finished drug preparations.

Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd business radiates to all levels, including direct supply cooperation with government departments and industry representatives, as well as establishing supply cooperation relationship with retail industry. We supply high quality, safe and effective medicines and medical equipment to governments, hospitals, clinics and licensed pharmacies in different countries with timely and effective services at reasonable prices.

At present Fuzhou FUL Fluid Equipment & Pharmaceutical Co., Ltd has the SINOPHARM authorization to sell its intermediates and APIs,and has the authorizations of CSPC & HUABEI PHARM sell its finished drug preparations;then FUL is the only manufacture in China which can supply the complete service from pharmaceutical produciton lines,intermediates and APIs to finished drug preparations and vaccines.Then we are seeking the professional pharmaceutical enterprices to work together for further cooperations.


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