Yeast Production Line, Fermenter Bioreactor (50L-10000L-ASME)

Feature description:
The cell reactor is used to complete the cell culture process from seed expansion to production culture, including the transfer and mixing of various materials, the precise control and display of temperature, pressure, pH, DO (dissolved oxygen), foam, liquid level and volume as well as the amount of alkali replenishment, replenishment volume, replenishment rate, the aseptic filtration, measurement and display of incoming air, oxygen, carbon dioxide and nitrogen (if any), the good control of condensation, heating and aseptic filtration of exhaust , the necessary online cleaning and sterilization operations during the production process, etc.
The ability to meet the temperature, pressure, pH, DO, foam and other requirements of existing production processes at the maximum working volume. The control of liquid level, cell density increased 5-15 times in 48h-72h after inoculation of CHO cells, with densities of 2.0×105Cells/mL-4.0×107Cells/mL. All parameters of the tank can be controlled.
The cell culture process from seed expansion to production culture, including the transfer and mixing of various materials, the precise control and display of temperature, pressure, pH, DO (dissolved oxygen), foam, liquid level and volume, as well as the amount of alkali replenishment, the amount of replenishment, the rate of replenishment, the aseptic filtration, measurement and display of added air, oxygen, carbon dioxide, nitrogen (if any); good control of the condensation, heating and aseptic filtration of emissions; the necessary online cleaning and sterilization operations in the production process.
 

Model: (automatically controlled sterilization), (manually controlled sterilization)

Material: 316L stainless steel liner and 304 sheath
Diameter and height ratio: 1:2-3 (customizable)

Mixing method: one of two options: magnetic stirring or mechanical stirring

Sterilization method: on-site sterilization automatic control or manual control

Control system: Siemens PLC, industrial LCD touch computer control, parameters can be set and stored, and can be connected to the computer remotely through the USB interface, data

Mixing system
Mechanical seal system: high-power stirring paddle, defoaming paddle; AC motor: continuously variable speed; speed in the fermentation tank: 70~1200rpm±1%, the height of the stirring paddle can also be adjusted.

Temperature detection and control
It is heated by a constant temperature water tank and circulated by a circulating pump (Glenfoss, Denmark), automatically controlled (cooling water + 5°C) to 65°C±0.1°C, temperature probe (USA)

pH detection and control
2.00-12.00±0.05pH, automatic control by adding acid and alkali, pH sensor (Switzerland Mettler) and shielded wire (Switzerland Mettler). The fermentation tank is automatically controlled by a peristaltic pump

DO detection and control
0-150±3%, display accuracy 0.1%, sensor (Mettler, Switzerland) and shielded wire (Mettler, Switzerland)

Feed control
Fermentation tank uses peristaltic pump (Longe) to add materials

Defoamer control
Pass sencor test and add defoamer through peristaltic pump

Intake control (air) manual control rotameter

Pressure detection and control
Pressure control: pressure gauge and digital display and digital remote control, pressure control

 

 

1. Are you a factory or a trading company?

Answer: We are a factory.


2. What is MQQ?

Answer: 1 unit.
 

3. Do you provide overseas services?

Answer: Yes, we can send engineers overseas.


4. Can we visit your factory?

Answer: Yes, you are very welcome.

 
5. What is your delivery time?

Answer: 2 weeks to 3 months. It depends on the size and quantity.