GMP Cefpirome Sulfate Injection 1.0g
Ingredients
The main ingredient of this product is: cefpirome sulfate.
Chemical name: (6R,7R)-7-[(Z)-2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido]-3-(6,7-dihydro-5H Cyclopentyl-1-ylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxy monosulfate.
Chemical Structure:
Molecular Formula: C22H22N6O5S2 ·H2SO4
Molecular weight: 612.66
Accessories: anhydrous sodium carbonate.
Character
This product is white to slightly yellow crystalline powder.
Adverse reactions
The following adverse reactions may be observed during cephalosporin treatment:
Allergic reactions: Allergic skin reactions; rashes, urticaria, itching, drug fever; severe acute allergic reactions may occur: angioedema, bronchial spasm, need urgent treatment. Examples of bullous reactions such as cephalosporins, erythema multiforme, Stevens-Johnson syndrome, and toxic epithelial necrolysis have also been reported.
Effects on the gastrointestinal tract: nausea, vomiting, diarrhea; rare cases may have pseudomembranous colitis (see special warnings and precautions for use).
Effects on lung function: There is the possibility of interstitial pneumonia (with fever, cough, dyspnea, chest X-ray abnormality, and eosinophilia) and PIE syndrome. If any of these symptoms occur, you should stop giving Drugs, take appropriate treatment such as adrenocorticotropic hormone.
Effects on liver function: Serum liver enzymes (such as aspartate aminotransferase (GOT), alanine aminotransferase (GPT), alkaline phosphatase), γ-GT, lactate dehydrogenase (LDH) and/or bilirubin are elevated. These laboratory abnormalities (which can also be caused by infection) rarely exceed twice the upper limit of normal and cause liver damage symptoms, usually cholestasis and often without symptoms.
Effects on renal function: There may be a slight increase in serum creatinine and urea, but in most cases there is no need to stop the treatment. Interstitial nephritis has been observed in individual cases during other cephalosporin treatments and rare acute renal failure has occurred.
Changes in blood composition: Thrombocytopenia; eosinophilia; rare hemolytic anemia. Like other ß-lactam antibiotics, neutropenia and rarex neutropenia are likely to occur during treatment with cefpirome, especially if the treatment is long. Patients with a course of treatment longer than 10 days should be monitored for hemograms (see notes).
Local reactions: Vein wall inflammatory irritation and pain at the injection site.
Neurological effects: Very few cases of convulsions have been reported. Like other cephalosporins, reversible encephalopathy can occur in large doses, especially in patients with renal insufficiency.
Effects on the cardiovascular system: bleeding, ecchymosis, and changes in heart rate.
Double Infection: Cefpirome, like other cephalosporins, may cause overgrowth of non-sensitive pathogens, including monoliasis, especially when used chronically. Repeated assessment of patient status is critical. If secondary infection occurs, appropriate measures must be taken.
Others: Abnormal taste and/or smell after injection, headache, fever.
Contraindication
This product is banned from allergic to cephalosporins, allergic to penicillin antibiotics should be used with caution.
Precautions
Renal function: This product should be given attention when combined with aminoglycosides or diuretics. All these patients should monitor renal function.
Renal insufficiency: The dose of this product should be adjusted according to creatinine clearance.
Pseudomembranous colitis: Severe and persistent diarrhea has been observed during and after several different antibiotic treatments. This may be a symptom of pseudomembranous colitis (most cases caused by Clostridium difficile), and severe cases can be life-threatening. This is a rather rare complication of cephalosporins. Once the diagnosis of pseudomembranous colitis (confirmed by colonoscopy) is considered, cefpirome therapy should be stopped immediately and specific antibiotic treatment (ie, vancomycin or metronidazole) should be started. Do not use drugs that inhibit intestinal motility.
Patients should be asked in advance if they have a history of ß-lactam antibiotic allergy.
Cefpirome is strictly prohibited for patients who have had a history of immediate allergic reactions to cephalosporins. If there is any doubt, a doctor must be present at the time of first dose to handle any possible allergic reactions.
Cross-allergy: Because 5%-10% of patients have cross-sensitization to penicillin and cephalosporins, cefpirome in patients with penicillin allergy should be performed with special caution. It is necessary to carefully observe the first dose.
The hypersensitivity reactions that occur in these two types of antibiotics can be quite severe or even fatal.
Hypersensitivity needs to stop using this product.
Blood components: If the course of treatment exceeds 10 days, blood should be monitored. If leukopenia occurs, treatment should be discontinued.
This product is forbidden to use for children until sufficient clinical experience is obtained.
Storage
Shade, seal, and store in a cool (no more than 20°C) dry place.
Our Advantages
1. Quick delivery
2. Online payment
3. Quality assurance
4. Welcome big order
5. After-sales service 24 hours
6. Competitive advantage products
7. Our value information is "Quality is our culture"
8. Work with us to provide you with secure funds, your business is securely protected, our advantages
After Sales Service
a) Free amples can be provided.
b) Guide customers through professional technology and teach them how to use our products after sale
c) Determine the lowest price of high-quality products
1. Skilled experience: Our company is a leading manufacturer of professional production in China pharmaceutical field for many years.
2. The highest quality: to ensure high quality, once any problems are found, the package will be re-shipped for you.
3. Safe transportation: by air express (FedEx, UPS, DHL, EMS). It is recommended that you choose the most professional freight forwarder.
4. Fast delivery: We have stock, so once payment is received, we can deliver quickly.
5. Quality service: We will provide you with enthusiastic after-sales service. If you have any questions, we will reply to youwithin 24 hours.
6. Competitive price: discounts will be obtained when making large orders.
FAQ
1.who are we?
We are based in Fujian, China, start from 2000,sell to North America(40.00%),Southeast Asia(25.00%),Western Europe(25.00%),Africa(10.00%).There are total about 50 people in our office.
2. how can we guarantee quality?
Always a pre-production sample before mass production;
Always final Inspection before shipment;
3.what can you buy from us?
Pharmaceutical production lines,Intermediates,APIs,Finished Drug Preparations & Vaccines.
4. why should you buy from us not from other suppliers?
We have our own manufacture factories and one professional sales team working for the clients all over the world.
5. what services can we provide?
Accepted Delivery Terms: FOB,CIF,EXW,DDP,Express Delivery;
Accepted Payment Currency:USD,EUR,CAD,AUD,GBP,CNY;
Accepted Payment Type: T/T,L/C,PayPal,Western Union;
Language Spoken:English,Chinese,Japanese
Company Profile
ITB Biopharm Co., Ltd is a comprehensive enterprise which integrates R & D, production and construction of pharmaceutical production equipments, development and transfer of biotechnology, and cooperative production and sales of drugs and vaccines. The self-developed pharmaceutical production equipment branded ITB has been put into operation in many well-known pharmaceutical enterprises such as SIN OPHARM, NCPC&CSPC and also cooperates with many well-known pharmaceutical enterprises in production and sales, including pharmaceutical intermediates, APIs and finished drug preparations.
ITB Biopharm Co., Ltd business radiates to all levels, including direct supply cooperation with government departments and industry representatives, as well as establishing supply cooperation relationship with retail industry. We supply high quality, safe and effective medicines and medical equipment to governments, hospitals, clinics and licensed pharmacies in different countries with timely and effective services at reasonable prices.
At present ITB Biopharm Co., Ltd has NCPC offical authorization to sell its Intermediates,APIs and Finished Prepartions which is produced by NCPC North Best and its own sister manufactures,then ITB Biopharm Co., Ltd is the only manufacture in China which can supply the complete service from pharmaceutical produciton lines,intermediates and APIs to finished drug preparations and vaccines.Then we are seeking the professional pharmaceutical enterprices to work together for further cooperations.
Factory View
Our Busines
Our Products
Audited Supplier 
){kind=link}
){kind=link}